Cell Cycle Inhibitors in Cancer Therapy (Cancer Drug Discovery and Development)
Leading clinicians and investigators review in a comprehensible and user-friendly style all the latest information about the molecular biology of …
Leading clinicians and investigators review in a comprehensible and user-friendly style all the latest information about the molecular biology of cell cycle control and demonstrate its clinical relevance to understanding neoplastic diseases. Topics range from Cdk inhibitors and cell cycle regulators to the prognostic value of p27 and tumor suppressor genes as diagnostic tools. Actual case studies show how the new molecular understanding has produced such drugs as Flavopiridol and Sulindac. The book brings all the recent critical research findings to bear on clinical practice, and clearly shows their powerful impact on the diagnostics, prognostics, and therapeutics of cancer, AIDS, and cardiovascular disease.
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2017年10月16日 - chemotherapeutic drugs target rapidly proliferating (cancer) cells ... receptor tyrosine-kinase including epidermal growth' factor receptor' and HER-P/neu ... in cancer, pre-clinical and clinical evidences of pan-CDK inhibitors and highly specific ... targets` for cancer-treatment and serious zone of research for.